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The study revealed variations in glucose utilization between the three cell lines.
A direct comparison between the three cell lines (MCF-7 [6], PC-3, and DU-145, Figure 4) reveals substantial similarities in dihydro-R biphasic proliferative action.
For the first two days, no significant differences between the three cell lines were observed.
Previous microarray analysis has suggested remarkably similar expression pattern between the three cell lines [28].
Comparisons of TAIII induced transcriptional changes between the three cell lines analyzed showed significant overlaps between BT474 and MDAMB231 (Table S2).
The number of protein identifications from total cell extracts in common between the three cell lines was 1179, and ranged from 2011 to 2267 for two cell lines (Figure 3A).
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There were also a larger number of fixed fluxes in the multi-tissue simulation, due to the higher interdependence between the three cell-specific models.
Multiple comparisons between the three cells types were performed using the non-parametric Kruskal-Wallis test.
*indicates significant difference between the two cell types (p < 0.05).
MET and EMT CSCs can readily transition back and forth between the two cell states.
A two-sample t test was also performed between the two cell lines at each density.
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