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where s i is the similarity value between the test compound and the i-th neighbor.
In this study, the AD is defined as a Tanimoto (or Euclidean) distance threshold between the test compound and its nearest neighbor.
Similar(58)
When the administration of test compounds is waterborne, one should consider the differences in solubility, stability, and means of transport to target tissues that exist between the test compounds and that influence the magnitude of biological response.
Hydroxyl radical scavenging activity was measured based on the competition between deoxyribose and the test compound (the plant extract) to react with hydroxyl radical generated from Fe2+/Ascorbate/EDTA/H2O2 system according to the procedure as previously described with slight modification [ 12].
Toluene was used as the test compound.
Inject the test compound via the cannula.
Docking results were evaluated by MolDock score function and hydrogen bond and hydrophobic interactions between tested compounds and the target receptor were used to compare between the tested compounds and the reference compounds (Table 3).
SUVs in the blood, liver, and kidney showed the strongest variations between the tested compounds.
An excellent correspondence between the experimental and modeled activities of the test compounds was observed.
A similar non-toxic effect was also observed in the cytotoxicity assay when CRFK, Vero and bovine dermis cells were exposed to the test compounds indicating no differences between the three cell lines with regard to their sensitivity to the compounds (Table 6).
The test compounds were dissolved inDMSO.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com