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Magnetic resonance angiography (MRA) was performed in all participants on two different study days with at least one week between the study days.
A fourth limitation is that the study was not designed to evaluate whether the differences found between the study days translate into improved patient care.
All blister wounds were covered with an air- and water vapour-permeable, self-adhesive dressing between the study days (Mepore; Mölnlycke Health Care AB, Göteborg, Sweden).
Moreover, we ensured that subjects had stable rest/activity patterns between the study days and controlled for the influence of eating and physical activity, both of which are known to have an impact on physiological rhythms.
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There was no significant difference in the number of unwell patients, based on markedly deranged physiological variables, being managed outside of the ICU between Summer and Winter on the study days analysed in our institution.
The interval between the two study days was four days.
As shown in Table 2, no differences were found in baseline plasma glucagon levels between the 2 study days in the RYGBP group.
Patients had a 30 min pH monitoring-free period, with removal of the catheter, between the two study days so that they could take a shower and change their clothes if they wished.
Because no significant differences between the 2 study days were observed, the combined data of both days were presented.
Differences in the total, summed, and peak headache scores between the two study days were analyzed using Wilcoxon Pratt's test.
The other EORTC QLQ-C30 scores were similar between the two study days (table 1).
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