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The observation probability of a given segment is represented as the relation between the segment likelihood and the estimation error of the trajectories.
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CNVs were called based on the absolute distance between the segment mean of each genomic segment and the median segment mean across all segments of each sample: Seg.dist j = | Seg.mean j − Median Seg.mean)|, where j stands for individual segments.
We assume deviations being independent between the segments and can thus define the negative log-likelihood for all segments in sample r as follows: There are a number of ways to exploit paired-end reads.
Two fold changes are compared: A) between the segments 3 1 and B) between the segments 3 2.
The gray matter segment was calculated from the difference between the cerebrum segment and cerebral white matter segment.
The higher the value, the higher the likelihood of the existence of a line segment between e i and e j.
This iterative process is performed until the absolute difference between the current likelihood and the previous likelihood is small enough.
However, in the event of a tunnel fire, the increased concrete strength of the segments increases their likelihood of spalling compared to segments fabricated by ordinary strength concrete.
The segment between Kingston and Marion was completed in 1915.
Otherwise, the segment between the peaks is assigned neutral state.
Candidate segments are the segments that have highly likelihood to be advertisement templates, while noncandidate segments have very low-likelihood values.
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