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The delay interval between the sample run and the choice run was approximately 10 15 s.
The time interval between the sample run and the choice run was approximately 15 s.
Increasing the length of the delay between the sample run and the choice run reduced the levels of alternation performance in both sham and OFC rats, but did so to an equal extent in both groups (Fig. 6B).
Testing then continued for all of the animals but with increasing delays of either 30 or 600 s interposed between the sample run and choice run of each trial.
This could presumably reflect the memory trace decay between the sample run and the point at which the mouse chooses which arm to enter on the choice/test run, or the confidence or certainty of the animal when making its choice.
Ventral HPC lesioned rats display absolutely no impairment on this spatial working memory task (Hock & Bunsey, 1998; Bannerman et al., 1999), even when there is a substantial delay (600s) between the sample run and the choice run of each trial (Bannerman et al., 2002).
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There was no additional delay imposed between the end of the sample run and the beginning of the test run; hence the automated task was performed at the pace of the mouse.
The filtration efficacies were calculated as a percent difference between the test sample runs and the control average using the following equation: % BFE = (C−T /C×100, where C = average of control values, and T = count of total for test material.
By extension, 3% of the length of the genome showed disagreement in CN Calls between the three sample runs.
However, automated spatial match/non match to position protocols in traditional operant chambers have been hampered by the fact that rodents often adopt mediating strategies to improve their performance [12,13,32], even when a supplementary task is included between the sample and test runs [33].
It has been reported that HPC-lesioned animals are particularly impaired in spatial non-match to place procedures when the interval between sample run and test/choice run is increased [10].
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