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None of these tests revealed significant differences between the respective expression profiles in SB and black.
However, remarkable differences were observed between the respective expression patterns in the embryo as well as in postembryonic tissues, arguing against complete redundancy [ 8, 12, 14, 15, 19- 22].
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Correctness of the respective expression constructs was verified by sequencing.
Data are presented as a relationship between gene expression in untreated MCF-7 or MCF-10A cells (defined as 100%) and the respective expression 48 h after treatment with 10 μg ml−1 adiponectin.
Then the respective expressions are matched in a uniform solution valid during the entire synthesis.
The distribution plots showed interesting differences between the respective gene expression profiles.
Both data sets (van de Vijver and BBCP) are preprocessed and clustered as follows: The logarithms of ratios between the respective gene expression to reference sample are scaled to [-1, 1].
Of particular interest is the close clustering of hESC-ECs and HUVECs, indicating a high degree of similarity between their respective expression profiles.
Though hESC-ECs and HUVECs revealed a high degree of similarity between their respective expression profiles, hESC-ECs do not resemble HUVEC completely.
The transcriptome of the mouse isochores for the three tissues (Additional file 1, Figure 1), the positive correlation between the isochores' GC level and their respective expression activity, and the increase of the average expression level of genes as the GC of the isochores increases support the existence of a relationship between expression level and base composition.
The median elevation of ISG15 expression in malignant cell lines vs. non-malignant cell lines was 2.5-fold and these differences in expression between the respective groups were statistically significant (p = 0.043, Mann-Whitney U-test).
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