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The relationship between the release profile and the rate of continuous water-phase addition is extremely complicated.
The relationships between the release profile and solubility of the drug and its permeability through silicone were also studied.
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In fact, the similarity between the release profiles of the MTP-CRG complex and the physical mixture, as opposite to DTZ, indicates that the interaction between MTP and CRG is overcome by that of MTP and water, indicating a weaker constant of formation/stability of the MTP-CRG complex relative to that of DTZ-CRG complex in water.
The nanocomposites containing 5%LATC30and5% 5% nHA showed an appropriate adjustment between the hydrolytic degradation and the release profile.
The release profile mainly depends on the drug release medium.
The release profile fitted zero order release kinetics.
The release profile then tended to plateau.
The release profile was derived based on the cumulative sum of released amounts at specific times.
The release profile showed a smooth and sustained release which was shown in Fig. 1c.
The release profile was determined using a dissolution test.
Concentration of plasticizer was found to affect the release profile.
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CEO of Professional Science Editing for Scientists @ prosciediting.com