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Linear regression analysis was performed to assess associations between the age and the proportion of CD45RC T cell subsets and to assess the association between the relapse and the proportion of CD45RC T cells subsets.
There was no significant differences in the tumour volume between the relapse and no-relapse groups.
The present study has demonstrated a clear difference in clinical features between the relapse and relapse-free groups.
Notably, miR-708 and miR-223 have the most significant differences between the relapse and CR patients.
Several correlations of differential gene expressions were discovered between the relapse and nonrelapse breast cancer samples, and most of them were involved in cancer regulation and cancer-related pathways.
Table S2 shows the average log2-fold change in the gene expressions of NFKB2, PTGS2, JUN, MMP1, RUNX1, CEBPA, and FIGF between the relapse and nonrelapse samples, which were 0.02, −0.13, −0.16, 0.7, −0.08, −0.01, and −0.09, respectively.
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The relationship between the relapsing and the progressive course of multiple sclerosis has remained ambiguous.
Principal component analysis (PCA) displayed no bias between and within the relapse and control groups (Additional file 2A-C).
There was no significant correlation between the localization of the relapse and the VEGF content.
The Mann–Whitney U-test was used for the comparative analysis of each angiogenic factor levels between the relapse group and no-relapse group and between the VEGF-positive group and the VEGF-negative group in evaluation of the biopsy specimen.
The correspondence between the actual relapse and the nomogram predictions suggests a limited calibration of the nomogram in the validation cohort.
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