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Exact(5)
No differences were found in mean hearing levels between the randomized and nonrandomized children: in both the randomized and nonrandomized children ventilation tubes improved the hearing level, especially after 6 months.
Student t-tests and regression analyses demonstrated no evidence of differences between either the operative and non-operative comprehensive cohorts, or between the randomized and non-randomised patients, at the 5% level.
However, the results of the sensitivity analysis did not show any difference in the efficacy of the treatment in relation to the type and quality between the randomized and non-randomized studies, and importantly, the absence of statistical heterogeneity or publication bias suggests that the results are robust.
We dealt with this validity threat by comparing patient demographics between the randomized and sequential design process, by including a design change variable in the regression analysis and by conducting an intent-to-treat analysis, which is useful for dealing with deviations in protocol.
The maximum number of gene relationships in common between the randomized and original data sets was five.
Similar(55)
This novel application of a penalized Cox model for adjustment of a trial estimate of treatment efficacy incorporates evidence-based estimates for other therapies, preserves comparisons between the randomized groups, and is applicable to other long-term trials.
The only statistical difference between the randomized treatment and control groups was percentage married (78 vs. 71%, P = 0.034; online appendix Table A2).
More patients reported serious AEs with placebo than empagliflozin, and the number of patients who discontinued due to AEs was similar between the randomized empagliflozin groups and the placebo group.
The agreement between the randomized networks tested here and the experimental data is no higher than 23.5%, roughly half as good as between the correct ODE model and experimental data (48%).
None of the measured demographic and hygiene characteristics differed significantly between the randomized groups (all p>0.10) (Tables 1 and 2).
Then, we measured the cross-correlation between the randomized sequences of formation changes and ({ w_{i,2}, ldots, w_{i,T_{i}-tilde {tau}}}) or ({ ell_{i,2}, ldots, ell_{i,T_{i}-tilde{tau}}}) using Eq. (15).
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