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Phylogenetic relationships between the query genome and SAR11 genomes represented in the metagenomic data are shown in Fig. 1.
The amino acid sequence divergence between the query genome we used and the Sargasso Sea SAR11 populations exceeds the divergence between some microbial genera, suggesting that genomic properties have had ample time to diverge in response to selection.
Similar(58)
Benchmarks were performed using a measure of similarity between the Gene Ontology (GO) terms of each functionally associated protein pair predicted in the query genome by each method.
Thus Ci is the CODA score for proteins p,q (pair i); the best (highest) score over all domain pairs between the proteins and over potential fusion proteins in all genomes (other than the query genome).
The single best coverage alignments were cleaned up by synteny when the query genome assembly was chromosome based and by reciprocal best alignments between query and target when the query genome assembly was scaffold based.
Hashing based aligners use hash trees or hash tables to store hash values of either the query genome or the reference genome and then use the un-hashed genome as a single probe against the hash table.
We first select some random positions on the query genome.
In cases where some HCEs have multi-alignment hits and some have no BLASTn hit in the query genome, two hits were looked as one pair according to the query genome, if there are less than two other HCEs located in between the two consecutive HCEs in the human and other species' genomes.
The set of gene families for this collection of Campylobacter genomes were found by BLASTing all proteins in each genome against all proteins in the query genome.
patens with C h. reinhardtii as the query genome.
One of the pathogenic fungal genomes is set as the query genome of interest.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com