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Moreover, we analyzed correlations between the predicted function terms and the 'true' terms.
We also found a close relationship between the predicted function of a gene and its tissue-specific expression.
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Circumstantial but crucial evidence in support of the psiRNA hypothesis comes from analogies between the predicted functions of CASS proteins and the protein components of eukaryotic RNA interference systems, in particular, the RISCs [ 7- 9] (Table 2).
Although all SNPs localized to genic regions, no obvious relationship exists between the predicted functions of these genes and Fusarium ear rot resistance; however the currently limited understanding of pathways contributing to resistance restricts our ability to predict what genes might be involved in resistance to this complex disease.
Although the total number of host defense proteins was similar in both milk samples, the predicted function of the individual proteins differed between species.
Finally, we examined the relationship between predicted function and d N/d S. Fisher's exact tests with FDR correction showed that genes with the highest d N/d S were not significantly enriched for any GO terms (neither genes in the top 5% nor 10% tails of the d N/d S distribution).
Figure 9 illustrates the histogram of the similarities between predicted functions and true functions of the tested genes.
Linear discriminant analysis (LDA) effect size (LEfSe: http://huttenhower.sph.harvard.edu/galaxy/) was utilized to evaluate differentially abundant bacterial taxa and predicted function between the animal groups.
We examined our predictions of gene function in both species and identified cases in which a pair of orthologs showed very large changes in predicted function between species (Table 1, full data in Table S5).
A relevant association was observed between the disordered residue numbers within predicted IDPs and their subcellular location, lack of transmembrane domains and lack of predicted function.
For the 20 proteins with predicted functions that do not match with their 'true' terms, the differences between the predicted terms and the 'true' terms may be due to incompleteness of the GO annotations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com