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To test the imprinting status of AK029869, we first identified useful SNPs between the polymorphic mouse strains PWK and C57BL/6 (B6) to distinguish the expression from the two alleles.
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Of the 320 markers screened, 173 are polymorphic between EM93-1 and US1, with the polymorphic rate being 54%.
This resulted in between 37 and 73% of the polymorphic markers being removed from the maps.
It has been shown that the susceptibility of different mouse strains is linked to the polymorphic locus Nalp1b [35].
In this study, the genic marker SNP3 was developed according to the polymorphic Gn1a sequence between Kongyu 131 and GKBR.
None of the polymorphic positions were changed between the different releases of the A. thaliana genome.
This map allowed ordering of the polymorphic markers and estimation of the distances between them.
Sequence context of the polymorphic miRNA-GDF8 interaction in sheep.
The polymorphic sites are underlined.
Similarly, the relationship between type of beta-defensin CNV block and polymorphic inversion awaits a large cohort typed for the polymorphic inversion.
These similarities in cytopathology between SBMA and our ESC model are surprising, because the length of polyQ tracts in the human AR gene is polymorphic, whereas the intrinsic mouse AR gene is not polymorphic and contains only 20 glutamine repeats, which the length of polyQ tracts is within the normal range (Supplementary Table S2), as verified by sequencing in several mouse ESCs.
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