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It was intriguing to know if there is a relationship between the polymerase sequence and cooperativity and oligomerization capacity.
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Genogrouping is based on phylogenetic relationships in the polymerase sequence.
Genotyping was primarily based on the polymerase sequence.
The NJ tree suggested no significant relationship between the HIV-1 polymerase sequences of the 6 HBV-A/G dual infected patients (not shown) suggesting that transmission of HIV-1 and HBV-G are independent events.
They also appear as inserts within the RNA polymerase sequences.
We utilized a series of oligonucleotides of defined sequence to define the interactions between the polymerase and exonuclease active sites.
Since a polymerase sequence of 8/DCC/Tokyo/JP/44 was not available in GenBank because of the unsuccessful amplification, homology in the polymerase region between HU/5862/Osaka/JP and 8/DCC/Tokyo/JP/44 was unknown.
For this we used sequences derived from the translesion DNA polymerase UmuC and the DNA replication initiation factor Hda that out of a panel of 15 peptide sequences were the most potent inhibitors of the interaction between the polymerase and clamp (Wijffels et al., 2004) (see Materials and methods for more details).
To better understand the relationship between the polymerase and exonuclease activities of UL30 (±UL42), we examined coordinated exonuclease and polymerase activity using a series of oligonucleotides of defined sequence (Table 1).
The P. nodorum RNA polymerase sequences were predicted from the genes on the following sequences: RNA Pol.
The P. ramorum RNA polymerase sequences were predicted from the genes on the following sequences: RNA Pol.
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