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The reported statistically significant gene sets exhibit only average consistency between the observed patterns of differential expression and known regulatory interactions.
Although our data clearly show an AT mutational bias in Hodgkinia, they do not directly implicate the force(s) responsible for the disparity between the observed patterns of mutation and substitution.
The dissimilarity between the observed patterns in cancer risk for pentachlorophenol and TCDD makes it unlikely that confounding by this compound is a reasonable explanation for the specific cancer risks seen with pentachlorophenol exposure.
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The strong congruence between empirically observed patterns in the ion distributions and anatomical structures extracted from the atlas indicate good spatial mapping between these data sources and strong biological signals in the IMS measurements.
The proposed temperature correction results in close agreement between the stimulated and observed patterns of diurnal variation for conditions ranging from clear to dusty.
pepgrep uses Peptide-to-MS2 modelling algorithm for scoring the match between reference and observed patterns in MS2 spectral data for y- and b-ion fragmentation profiles.
We scaled discrepancies between the observed and simulated patterns with a transformation of the variance covariance matrix of the observed pattern to objectively identify patterns that are "close".
However, uncertainty in tomography models appears not to change the overall patterns of the simulated sections, as shown in Fig. 4. Therefore, when we observed inconsistency between the observed and simulated patterns in the overall features, it was likely due to uncertainties in the latter procedure.
The difference between the observed and fitted patterns is indicated by the blue line at the bottom of the figure while the green line shows the fit to the background.
Based on the idea that gene expression levels are regulated by the combinatorial actions of multiple transcription-factor binding motifs, we formulated a linear relationship between the observed gene expression patterns and the appearance number of potential transcription-factor binding sites in the regulatory region of each gene.
If the two truck type distribution patterns are similar to each other, a match between the observed truck type distribution pattern and the expected truck type distribution pattern is expected and thus the null hypothesis cannot be rejected.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com