Sentence examples for between the native fold from inspiring English sources

We show, on the other hand, that three of the examined models are nonetheless capable of discriminating between the native fold and many nonnative alternatives, a test commonly used to validate force fields.

The ProSA Z-score can hardly be used as a measure of absolute model quality as it is highly dependent on the protein size (i.e. the energy gap between the native fold and random decoy structures increases with protein size).

Since the Rosetta energy function24 has a global minimum at the native fold, lower-energy models should also exhibit higher convergence towards the native structure.

The native fold of the ribozyme is complex, having two pseudoknots.

The native fold remains intact up to 70 °C, although thermal denaturation is irreversible.

Despite their postulation as incompatible elements with the native fold, these mutations rarely modify the native state structure.

As the example shows, loss of native contacts (smaller c) lead to model structures with lesser geometric similarity to the native fold (smaller f).

The native fold of inhibitory serpins is metastable and conformationally labile (Cabrita & Bottomley, 2004).

However, whereas the native fold displayed a Ki of 1.7 nM, the ribbon fold was 380-fold less potent (Supplementary Figure 1).

Hence, sequence-specific interaction energies between pairs of protein fragments have been derived from a statistical analysis of the native folds of globular proteins.

The z-score is the ratio of the difference between the lowest native fold energy and the average energy of all folds to the standard deviation of all fold energies.