Sentence examples for between the native conformation from inspiring English sources

For proteins with non-functional equilibrium intermediates, determining the relevant stability of the protein (the free energy difference between the native conformation and the intermediate) is most important, and it allows very valuable structural information on the intermediate to be derived when protein variants are compared to wild type using equilibrium ϕ-analysis.

The parameters of the distance-dependent energy functions (OSCAR-dstar) were initialized to the corresponding values (OSCAR-d) previously optimized, by maximizing the energy gap between the native conformation and rotamers at each modeled position (Liang et al., 2011a).

Conversely, interactions between U2585 and the P-site substrate might well stabilize the native conformation and hence suppress the conformational change required for SA binding, contributing to the poor inhibition by SA of ribosomes engaged in protein synthesis.

The measure of model accuracy is the local backbone RMSD, calculated by superimposing the stems of the loops (as described before) and then calculating the RMSD of the H3 loop main chain atoms between the model loop and the native conformation.

We have used flow cytometry to study the interactions between the antibody and ADAMTS13 so that the native conformation of the ADAMTS13 protein could be preserved.

Moreover, most models are clustered between 1 and 5 Å away from the native conformation, with an average of around 2.5 Å, which is exactly similar to the estimated error in atomic position of the native GC pilus model.

Our results show that the fusion protein is a monomer in aqueous solution, forms a stable intramolecular complex, and likely retains the native conformation of the complex between Bcl-xL and the HBx BH3-like motif.

MIRA-1 was described to shift the equilibrium between the native and unfolded conformation of p53 towards the native conformation, leading to restoration of p53-mediated transactivation of target genes and induction of apoptosis in a mutant-p53-dependent manner [ 83].

The native conformation is ranked #35 out of 248 structures (14%).

In addition to the native conformation, a protein sequence populates small fluctuations around the native state, partially unfolded forms and even the globally unfolded conformation.

The results showed PFSi NPs could essentially maintain the native conformation of GOD.