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There was no apparent difference in non-adipocyte material in the sections between the mouse groups.
While gene ontology (GO) analysis and functional annotation were pointing consistently to differences in metabolic responses between the mouse groups, they did not indicate which individual pathways were affected.
In male mice no difference in carcinoma development was found between the mouse groups.
At the highest concentration used in this study, most of the hair cells were lost and we observed no differences between the mouse groups.
No differences were detected between the mouse groups in VDAC quantity (VDAC immunoblot Fig. 8b, γ-sarcoglycan control Fig. 8c, and quantified in Fig. 8d).
The number of foot processes of the podocytes did not differ between the mouse groups, indicating that the foot process effacement of the podocytes was affected to a similar degree in both mouse groups.
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The statistical analysis performed using Fisher's exact test showed that the difference in TFF between the mouse group receiving 3 MBq/mL of 213Bi-MX35 and the control group and between the group receiving 9 MBq/mL of 213Bi-MX35, and the control group was statistically significant (p = 0.02) and (p = 0.0002) respectively.
In HL60/ADR-control shRNA group, there was no significant difference in tumor volumes between the mice groups with and without drug treatment, but in HL60//ADR-B4GALT1 HL60//ADR-B4GALT1r volumeshRNAe found to decrease sigroupcantumorith drug treatment in comparison with that of the mice group without drug administration.
Colon tissue samples were fixed in 10% formalin and undergo histological scoring by H&E staining to detect and compare cellular infiltration, depletion and damage between the different mouse groups.
Both heart-to-body weight and heart weight-to-tibial length ratios were comparable between the two mouse groups.
Little difference was identified for either cardiomyocyte size (H&E staining) or interstitial fibrosis (Masson's trichrome staining) between the two mouse groups (Fig. 1D).
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