Interaction effects were evaluated by testing for the direct interaction effect by including the centered product of BMI by MCP-1 and performing the association analysis between MCP-1 and the kidney function measures stratified by BMI where the sample was stratified into two subgroups (non-obese: BMI <30.0 kg/m and obese: BMI ≥ 30.0 kg/m).
The correlations between the structural parameters and the kidney function in healthy as well as in chronically injured kidneys, suggest that these parameters in the future may be used as surrogate markers of kidney function.
We compared the strength and independence of the association between each kidney function measure and the renal dysfunction across the best, intermediate and worst groups.
The relationship between kidney function and the extent of drug exposure is best exemplified by carboplatin, where the dose of drug administered is determined by renal function in both adult and paediatric patients (Calvert et al, 1989; Newell et al, 1993; Thomas et al, 2000).
The discrepancy between estimated kidney function calculated by the Cockcroft-Gault equation, the abbreviated MDRD Study equation and the CKD-EPI equation highlights the need for better methods to easily and accurately evaluate kidney function in the clinical practice setting with results readily available to all providers, including pharmacists.
The interaction between baseline kidney function and the performance of biomarkers of acute kidney injury (AKI) on the development of AKI is unclear.
Although monogenic causes of nephrolithiasis frequently result in ESRD [ 11], the relationship between impaired kidney function and the common type of kidney stones is much less clear.
To reveal the underlying molecular mechanisms for the difference between genders in kidney function, the gender-dependent gene expression in kidneys of three groups of 36 day-old rats was evaluated with microarrays.
The mechanism through which UA is regulated by the kidney and the relationship between UA, kidney function, and CVD are not fully understood [ 7].
This study is the first population-based study showing that the association between kidney function and CAC depends on age.
