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Further differentiation produces a thin layer of cells, called the hypoblast, between the inner cell mass and the cavity.
To examine the relationship between the inner cell mass (ICM) grade and its morphological configuration on the occurrence of monochorionic diamniotic (M-D) twinning.
In the mouse, enhancer-specific regulation of Oct4 expression is a defining molecular distinction between ESCs and EpiSCs in vitro (Brons et al., 2007; Tesar et al., 2007) and between the inner cell mass (ICM) and postimplantation epiblast in vivo (Yeom et al., 1996).
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A cavity appears in the morula between the cells of the inner cell mass and the enveloping layer.
The divergence of lineages between the trophectoderm and the inner cell mass in the preimplantation mouse embryo is dependent upon both intrinsic and extrinsic factors.
Thomson, J.A. & Solter, D. Chimeras between parthenogenetic or androgenetic blastomeres and normal embryos: allocation to the inner cell mass and trophectoderm.
When removed and grown in the lab, cells from the inner cell mass are called embryonic stem cells.
The cells of the interior, the inner cell mass, develop into the embryo proper.
A stem cell state that resembles that of the inner cell mass of the blastocyst.
Inside the sphere is a blob known as the inner cell mass which contains the stem cells.
Oct4 immunostaining not only marks pluripotent cells but also indicates the inner cell mass of blastocysts25.
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