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This is achieved by a least squares minimization between the initial experimental and numerical shapes.
Some discrepancy between the initial experimental data points and the simulations was observed for both metabolites, which could be an indication of a damped oscillation with rather high amplitude.
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How risky was the initial experimental goal?
The initial experimental concentration was approximately 104 CFU/mL.
RR assisted with the initial metabolic reconstruction and model generation, and the initial experimental fermentation studies.
XF and XC performed the initial experimental design, participated in the experiment, performed data analysis, and wrote the initial manuscript.
Kristy Horan conducted the initial experimental optimization of the microinjection procedure.
DBK and SGO conceived the project and the initial experimental design.
This result reflects an enrichment = 232/824 × 144,475/1,356 = 30 relative to the initial experimental HTS hit rate.
To include typical experimental pretreatments, we allow the initial conditions x0 u, θ) to depend on the system parameters θ and initial experimental influences u.
In research, experimental results must be shown to be reproducible to be claimed as valid and the first clause to ensure consistency is to provide identical initial experimental conditions between trials.
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