Your English writing platform
Discover LudwigSuggestions(1)
Exact(3)
Connections could then be built between the individual pathways based on shared pathway members and common interactions.
The main transcriptional response indicates a tight interconnection between the individual pathways of the glucose regulatory system.
In general, the Wnt pathway is divided into the canonical/ β-catenin dependent pathway and the non canonical/ β-catenin independent pathways (including the planar cell polarity pathway and Wnt/Ca2+ pathway), though it is now understood that there is significant overlap and cross-talk between the individual pathways.
Similar(57)
In order to test this hypothesis we represented the relationship between individual pathways (defined by their degree of overlap) using hierarchical clustering.
With the need to respond to and integrate a multitude of external and internal stimuli, plant signaling is highly complex, exhibiting signaling component redundancy and high interconnectedness between individual pathways.
Detailed analysis uncovers established and new relationships within and between individual pathways and their members.
It is now understood that traditionally defined singling pathways are not functioning in isolation but rather form whole signaling networks involving crosstalk between individual pathways.
This response varies in direction to mimic either a high or a low glucose response and reveals both known and unknown relationships within and between individual pathways and their members.
SAM-GS is another geneset enrichment analysis method based on the t-like statistic for assessing the permutation-based significance of association between an individual pathway and a phenotype of interest.
To test whether these pathway-specific modules can be detected in the context of the expression of the entire genome, and to determine whether genes other than those encoding catalytic functions of the pathway are co-regulated, we calculated Pearson correlations between individual pathway-specific hub genes and the 22,746 genes represented on the Affymetrix chip.
The extensive cross-talk between the different signaling pathways makes it difficult to assign individual pathways to specific responses; in a cell-type and context-dependent manner, several signaling pathways contribute to each of the cellular responses.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com