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They allow measuring the gap between the indication of therapies that have proven effective within human clinical research and the real safe and effective use of these therapies in routine clinical practice.
In metrological terminology, an interference is an influence quantity, defined as a "quantity that, in a direct measurement, does not affect the quantity that is actually measured, but affects the relation between the indication and the measurement" (7).
First, the association may be due to indication bias (11); that is, the true association may not be between the medication and the outcome but between the indication for the medication and the outcome, in this case between depression and incidence of diabetes.
Similar(57)
He added, "Between the indications of weapons work, which would constitute a violation of Iran's treaty obligations and Iran's blatant violations of Security Council resolutions, there is strong reason for Iran's file to remain open both in New York and in Vienna".
As the treatment of patients with schizophrenia is partly carried out by general practitioners in Germany, the total costs incurred for the treatment of this illness should be located between the indication-specific and overall costs.
The biomechanical evidence of finite element evaluations combined with clinical evidence will distinguish between the indications for plate or screw fixation in vertically unstable posterior pelvic fractures.
Based on our experience, there is no difference between the indications for scleral buckling surgery conducted under a surgical microscope and those for conventional scleral buckling surgery.
One particular challenge is the inability to adequately assess the sedation level, and to distinguish between the indications for sedation and for pain relief, due to the reduced level of consciousness.
For consistency between the indications provided by the current guidelines for the management of severe sepsis and septic shock [ 1] and for the calculation of the SOFA score [ 10], the cardiovascular SOFA subscore was modified by lowering the mean arterial pressure limit to 65 mmHg for point 1.
However, in our analysis, we found no association between prevalence of the indication and market authorisation.
However without a statistical difference between the groups, the indication is that both CURSI/CURASI and CRSI perform at least as well as CURB-65 or CRB-65, respectively.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com