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No significant difference was found between the groups given single agent gemcitabine at 11 or 23 HALO.
In the current trial, however, no statistically significant difference was found in ICP monitoring between the groups given progesterone or placebo.
The Fine and Gray multivariable analysis also showed that IBTR incidence differed significantly between the groups given and not given radiotherapy (p = 0.041) and that the effect of radiotherapy on IBTR differed significantly between the pT1 and pT2 4b groups (p = 0.014 for axillary dissection × pT interaction) (data not shown).
The majority of the upper-GI AEs occurred in patients with a history of GI disease; there were no significant differences between the groups given risedronate and the group given placebo in the incidence of upper-GI AEs in these patients.
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The ICER is the difference between the costs and effectiveness of the groups, given by δ1/ β1.
On the basis of data from previous studies, this study was designed with 80% power to detect a 30% absolute difference in anti-Xa levels between the groups, giving a total sample size of 80 patients.
The regression-based estimates using imputed data and adjusting for baseline differences between the groups gave similar results: over four months, mean estimated costs were £38 cheaper but mean estimated QALYs were also 0.02 lower in the decision support arm than with usual care.
In immunocompromised patients admitted to the ICU with acute respiratory failure, the need for noninvasive or invasive mechanical ventilation within the first 2 h was not significantly different between the group given high-flow nasal oxygen therapy and the group given oxygen via a Venturi mask.
The overall test for differences in stem cell frequencies between any of the groups gave a Chi-Square score of 142 (p = 1.29 × 10-30).
There was no significant difference between the untreated control group and the group given i.p. saline.
Importantly, there was no difference in weight between the two HSA groups and the group given BiP + anti-IL-10.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com