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However, no obvious differences between the genotypes could be seen (data not shown).
The reason for the difference between the genotypes could be the incomplete normalization of cbb1 plants.
The variation in expression levels between the genotypes could clearly be separated into two categories; high and low expression levels with almost a 1 1 segregation pattern.
The sustained cold exposure resulted in pronounced changes in BAT morphology, food intake, body weight, weights of BAT and WAT, and body temperature, but no clear differences between the genotypes could be observed.
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Mmp3 was expressed, but no differences between the two genotypes could be determined (Fig. 4a).
No significant differences in total weight or size between the two genotypes could be observed (Fig. 1a).
In summary, neither melanocyte targeted HDGF-overexpression alonor nor in combination with a second genetic alteration and/or UVB-treatment, led to the development of melanocytic hyperplasia, or lesions in which differences in melanocyte number between the analyzed genotypes could be observed.
As differences in PK/PD between genotypes could change the effects of the drugs, we compared the levels of drugs in brain and plasma of treated versus untreated groups and treated mutants versus WT mice.
Heterozygous loci polymorphic between two genotypes could be used as anchored markers suitable for comparative genetic maps (sinteny).
If there is a direct fitness benefit to territorial success, intransitive patterns of success between genotypes could maintain variation in aggressive strategies.
If this kind of G × G interaction is in play, then significant differences in variances of phenotypic trait scores between genotypes could provide evidence that a gene may be implicated in epistasis.
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