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The sampling points were different between the genotypes because of the different durations of fruit development.
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As these mice got older, the difference between the genotypes decreased primarily because the activity of normal animals declined (Figure 2B).
The genotype 1a and 1b samples were analyzed separately because sequence variation between the genotypes was anticipated to be larger than differences associated with response to therapy.
The distributions of genotype frequencies were compared between the genotypes of the SNPs and migraine-related characteristics.
Response to treatment differs between the genotypes.
Adipocyte size was similar between the genotypes.
In cases when even both genotyping primers had a perfect match with the template DNA, genotyping failed also simply because an intron was predicted to be present between the genotyping primers.
Because the 'genotype block' contained only the FCA scores as a single variable, we could directly visualize the relationship between the genotype (one variable = FCA score) and the morphology block (one variable distilled from the geometric morphometrics data).
To compensate for any changes in epithelial content in whole tumors between genotypes, because only the tumor epithelium is deleted for Hif1a, Ints3-normalized Cp values were also normalized to Krt18 (cytokeratin 18).
The constraints we have imposed through our strategy would necessarily underestimate the number of varietal SNPs between genotypes because our approach i) cannot identify varietal SNPs located in regions unique to either the At or Dt genome, as our SNP calling relies on the presence of both At and Dt reads; and ii) will miss the genuine varietal SNPs without a flanking subgenome-specific SNP.
Interestingly, with a high fat diet the significant difference between both genotypes declines, because the wild-type mice also become obese.
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CEO of Professional Science Editing for Scientists @ prosciediting.com