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Exact(17)
We found that markers such as CD34, CD68, and collagen do not effectively discriminate between the four cell types.
A one-way ANOVA and Tukey's Multiple Comparison Test were used to compare mean σ between the four cell lines (Fig. 4).
It is the concentrations of these molecular species that vary most significantly between the four cell lines.
A good separation between the four cell lines can be achieved by utilising just the first three PCs.
The percentage of cells undergoing apoptosis at any given time differed markedly between the four cell lines.
Among computed colony indices, 'Colony Elongation' and 'Mean Edge Length' were identified to be discriminative between the four cell lines.
Similar(43)
Sequencing depth was comparable between the two cell types displayed.
Further, the transwell migration assay was performed to determine the differences between the two cell lines.
Control groups included constructs where direct contact between the two cell types was prevented.
Besides these global similarities between iPSC-Mac and PBMC-Mac, direct comparison between the two cell types revealed several differentially expressed genes (DEG) (Fig. 2e).
The results reveal key differences in methylation patterns between the two cell types, suggesting potentially different gene regulation mechanisms in pluripotency and differentiation.
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