Sentence examples for between the estimated binding from inspiring English sources

Whereas PharmDock provided a high Pearson correlation coefficient between the estimated binding energy and experimentally measured binding affinities compared to other programs, the overall binding affinity prediction is still not accurate enough for drug optimization purposes.

We validated the effectiveness of our model in capturing non-binding influences and separating them from the ChIP-seq signal by showing it leads to a better ranking of peaks and a better correlation between the estimated binding signal and motif frequencies.

Edges were assigned a base-weight of | r ij |, or the absolute value of the Pearson correlation between factors i and j and then weighted by the estimated binding potential, b ij, between the two genes.

To construct a network, the estimated binding energy between the TF and every possible site in intergenic regions is obtained.

In contrast, the estimated binding affinity between Rox-DrpC and mD1 was greater than 70 μM, suggesting not only that the Dvl PDZ domain binds intrinsically to the Dvl C-terminus but also that this binding interferes with interactions between the Dvl PDZ domain and its other binding partners in the Wnt signaling pathways.

We refer to this as the estimated binding signal (B).

The estimated binding affinity indicated whether or not the predicted binding site is favorable for drug binding.

Pure Monte Carlo methods can estimate binding to loose protein cavities but can be inefficient, given the rugged energy profiles of binding and the large binding space occupied by clashing between ligand and receptor.

The estimated results of binding free energies are qualitatively comparable to binding affinities observed in experiments.

This value is comparable to the estimated per pair aggrecan aggrecan binding strength (≈1 pN) between two opposing end-attached aggrecan layers.

In fact, for small data sets, there is a strong correlation between the mean binding site number in a data set and the estimated λ/μ ratio.