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We can not be certain that the effect on survival we observed (shown in Figure 5b) is due to the differential protein levels between the differentiated and starved cells in the two cell lines, or to the overall two-fold elevated levels of HSP90α in the HC11-HSP90α HC11-HSP90α
Developing neurons travel toward the olfactory bulb along the RMS via glial tubes, which mark the division between the differentiated nervous tissue and the tissue with embryonic characteristics.
The POMC mRNA expression was not significantly different between the differentiated hypothalamic neurons and the undifferentiated neurospheres from where the neurons were obtained (86.64±27.86 a.u. and 89.02±48.34 a.u., respectively) (Figure 5-F).
However, HNT expression is not significantly different between the differentiated microcell hybrids and the parental cells.
We then investigated whether the amount of HSP90α differs between the differentiated and starved cells.
There was not a significant difference between the differentiated and undifferentiated type (p = 0.8387).
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A considerable number of the genes involved in the diversity between the poorly differentiated carcinoma and highly differentiated papillary adenocarcinoma tumors are associated with the nucleoplasm and the plasma membrane.
A statistically significant difference was observed between the highly differentiated group and the poorly differentiated group (P < 0.05).
The first cDNA encoding a subunit of the hPAF complex, hPaf1 (AJ401156), was identified in our laboratory as a differentially expressed mRNA between the poorly differentiated human pancreatic tumor cell line, Panc1, and the well-differentiated cell line, CD11 [13].
The fold change (FC) values were calculated by the ratio of the geometric means of the gene expression levels between the well-differentiated and poorly differentiated groups.
This meristem, a relic of the procambium, is composed of thin-walled cells, is flattened in the radial plane, and persists between primary vascular tissue, the differentiated outer phloem, and the inner xylem.
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