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Recent studies with NS3/4A protease inhibitors have shown that the genetic barrier and resistance profiles substantially differ between the different genotype 1 subtypes.
Although the -819T allele is also associated with lower LPS-induced IL-10 production, no significant difference was found between the different genotype groups (Table 4).
Log-rank test and Cox proportional hazard models were used to compare SPM-free survival and SPM risk between the different genotype groups.
Log-rank test and Cox proportional hazard models were used to compare SPM-free survival and SPM risk between the different genotype groups.The authors found significantly reduced SPM-free survival for patients with variant proline (Pro) 72 allele compared with patients with arginine (Arg) 72 homozygous genotype (log-rank test, P =.005).
The nonparametric test, Kruskal-Wallis test, was used to compare mean age of diagnosis between the different genotype polymorphisms.
Antibody levels against CCP (CDK6, PADI4 ) and cit-Vim (PTPN22 ) were compared between the different genotype groups.
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Furthermore, investigation of splenocytes showed no significant differences between the different genotypes used in this study in regard of inducibility of apoptosis, cell subsets and production of cytokines (see Material S1, Figure S1).
We did not observe any differences between the different genotypes during the behavioral task.
As to the CD4-cell response, there were no significant differences between the different genotypes and haplotypes, either.
There was no difference between the different genotypes, indicating equal activity of these mice under test conditions.
In samples that underwent enzyme hydrolysis without pretreatment, both phloem and pith cells were completely disrupted, and there were no significant differences between the different genotypes.
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