Your English writing platform
Discover LudwigExact(1)
2, 3 Indeed, many connections exist between the deacetylation function of SIRT1 and its role in neuroprotection.
Similar(59)
Whereas the early interaction between SIRT6 and PARP1 likely functions to stimulate the repair process, it is possible that this later wave of histone deacetylation functions to restore the original chromatin structure of the locus or to condense chromatin to prevent further damage.
In order to test whether there is function enrichment for the deacetylation partition groups, the following procedure was performed.
Chitosan is a semi-crystalline polymer, and the degree of crystallinity is a function of the deacetylation level.
HDAC6 is a class-IIb histone deacetylase located mainly in the cytosol, which displays diverse functions through the deacetylation of multiple substrates [ 19, 55].
In mammals, a consequence of the interaction between Sir2 and p53 is the deacetylation of p53 [ 15, 16, 17].
Sirtuin 3 (SisT3) is a key regulator of mitochondrial functions that result in the deacetylation of many enzymes involved in central metabolism, regulating numerous metabolic pathways.
Phylogenetic analysis suggests that HDACs evolved before histones and a major function of these enzymes is the deacetylation of non-histone substrates.
SIRT1 counterbalances the HAT function of CLOCK by deacetylating both H3 Lys9/14 and BMAL1, 48 as well as the deacetylation of the circadian regulatory protein PER2.
To further confirm it is the deacetylation status of TFEB that facilitates fAβ degradation by upregulating lysosomal function in microglia, we also evaluated the effects of TFEB-K116Q mutant (acetylation mimic).
However the deacetylation sites can reduce this correlation between the physical distance and the expression similarity.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com