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Comparison between the current data for water jet and the model of Zhao et al. [8] (Equation 1) and Teamah and Farahat [10] (Equation 2) are shown in Figures 7 and 8, respectively.
There are some disparities between the current data and previously published work on MCK-Cre+/− PTEN−/− mice.
The differences between the current data and our previous findings most likely relate to differences in our statistical management of the dataset.
In total, the limited number of incongruities between the current data set and the literature are thus largely reconcilable.
Next, we compared the number of AS events per gene between the current data set and TAIR.
The most significant factor to account for the difference between the current data and that previously reported was that 52% of the patients in the preliminary analyses were premenopausal at baseline, compared to 36% in the present data set and these women were significantly more likely to experience a treatment-induced menopause (OR 3.12, P=0.016).
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A first implication of our results is the possibility that some of the mechanisms responsible for the observed differences between ASM and VFM still affect the Current data regardless of the version used (either 0405 or 0408).
Several explanations could underlie the apparent inconsistency between previous findings and the current data, including the fact that experiments involved different animal species (rodent vs. primates).
The methodologic differences between previous studies and the current data are important to interpretating the data.
Given the prevalence rate of 76.7%% observed in Polish pregnant women hospitalized at the same department in the earlier period between 1999 and 2009, the current data revealed a decrease in the HCMV prevalence rate in the recent years [ 3], being similar to that for pregnant women in Spain (57 %), Norway (60 %), and Italy (68 %).
This controversy, however, is at least partially resolved in a combined analysis using the Bayesian methodology in Section 4. Figure 1 genuinely establishes the general importance of the issue of compatibility between the historical data and the current data.
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