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Finally, other programs such as ACGT [ 77], GOAL from BROP [ 78], BugView [ 79], and GenomeComp [ 80] have contributed to the field of comparative genomics by linearly representing rearrangements or syntenic information by linking homologous regions between the compared genomes using lines.
The distance is the minimal number of split events identified between the compared genomes.
Finally, the boundaries of the RGP were homogenized between the compared genomes and potential insertion sites were defined.
For CDSs, found orthologues were linked to their genome position to evaluate synteny (i.e., a conserved order of orthologous CDSs between the compared genomes).
The resulting averages reflected the degree of evolutionary distance between the compared genomes, and a value of higher than 94% ANI could represent the DDH boundary of higher than 70%.
Genomic comparisons have identified genetic variation for population screening; however, these analyses are limited to those sites that vary between the compared genomes and are potentially misleading (13 – 15 ).
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Not surprisingly, both the number of intron pairs compared and the number of U12-type introns conserved between the human and the compared genomes decrease with the phylogenetic distance.
Figure 2 indicates the segments of pronounced colinear similarity between the compared genome pairs at the nucleotide level and suggests that patches of external DNA have been added to a conserved genomic core.
Because microsatellite sequences mutate under a stepwise model (Estoup et al. 2002), the differences in allele size between two microsatellite DNA copies measured either within or between individuals is related to the coalescence time and hence the level of divergence between the two compared genomes.
To test for possible association between replication origins and synteny breakpoints, we checked if at least one of the genes in the 8 kb region corresponded to an extremity of a synteny block between the two compared genomes.
However, many exceptions to this trend could also be found resulting and an overall lack of correlation between the AAI between two compared genomes and the number of linked fragments (R2 = 0.006; P = 0.061).
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between the compared models
between the compared samples
between the compared variables
between the compared algorithms
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between the compared values
between the compared architectures
between the compared clusters
between the compared conditions
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between the compared results
between the compared alternatives
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between the compared profiles
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