The limited genetic differentiation between the cluster from the Pacific coast and the central Colombian valleys (clusters 2 and 1, respectively), evident from the PCoA scatter plot (Fig. 2d), suggests that the former may represent a recent introduction, possibly even of anthropogenic nature.
Accordingly, the probability of homology between the genes inside the clusters from the two genomes is significantly higher than (i) the probability of homology between the genes outside the clusters or (ii) the probability of homology between the genes inside the clusters and the genes outside the clusters (P = 6.2 × 10 121, χ test).
DOI: http://dx.doi.org/10.7554/eLife.06474.016 10.7554/eLiFigure74.017 Figure 5 figure supplement 1. Distance distribution between the centers of each of the clusters from the SpoIIIE-Dendra2 dual foci in ΔσE strain.
Spacings between the clusters range from 14.5 to 340 m.
Characterization was applied to reveal the difference between the clusters obtained from the different precursor types.
On focusing on the clusters, including transcription factors, characteristic relationships between the clusters emerged from the associations of the clusters within and between the four phases; one of the remarkable features is the distinctive relationships for the clusters between neighboring and non-neighboring phases.
The square inserts in (B and C ) show overlap between the clusters resulting from the whole brain group comparisons (orange) and the controls' hand area (white), as shown in (A ).
These authors applied SVD to clusters ('modules' in their terminology) of expression profiles identified separately for several brain regions, and demonstrated conservation of 'module membership' between the corresponding clusters from different regions.
The Bayesian inference, maximum-likelihood, and maximum-parsimony analyses identified the cluster from Spain and EBLV-1a and EBLV-1b as being monophyletic, although only maximum-likelihood and maximum-parsimony analyses suggested a closer relationship between EBLV-1a and the cluster from Spain.
Moreover, the difference between wild type and prohibitin-depleted worms is higher at the YA than at the L4 stage, as shown by the distance between the clusters in the dendrograms derived from the supervised models (Fig. 3D and E).
