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This effect is most clear in low salt conditions, which destabilize dsDNA by reducing the screening between the charged backbones.
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This was due to that the repulsion between the negatively charged backbones of DNA strands and [Fe CN 6]3−/4− hindered the interfacial electron transfer.
B-DNA double helices can form tight crossovers in crystals where the electrostatic repulsion between the negatively charged backbones is minimized.
5) The sentence "When the highly negatively charged backbone of rRNA polynucleotide chain….with charge of the RNA backbone" (Page 2 second paragraph) is very speculative.
The NSS at MARS2 position 345 was in close proximity to the tRNA negatively charged backbone.
So, there should be some degree of electrostatic repulsive interactions between SRM and negatively charged backbone of ssDNA.
The change in shape of the response curve is due to changes in the structure of single-stranded oligonucleotide when potential is applied and results from interactions between the charged oligonucleotide phosphate backbone and the gold surface and hydration shell dynamics.
They demonstrated that glycopeptides with a negatively charged backbone showed enhanced inhibition as compared to the other conjugates.
According to the NMR structure [ 22], the K104 side chain is directed away from the beta sheet, an orientation that would make possible interactions between the charged amino side-chain and the RNA backbone.
Electrostricted water is associated with hydration of the charged phosphate backbone.
In the case of protonated lysine dipeptide, looking for outliers allowed us to reveal the presence of conformers with different chemical connectivity, or of strong H-bonds between the backbone and the charged side chain.
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