Sentence examples for between the binding pocket from inspiring English sources

In our recent study [44], we explored the complex intermolecular interactions between the binding pocket of HLA-B*57 01 HLA-B*57 01ding drug abacavir, and theee co-binding peptidrugfrom the three abacavire X-randcrysthree(PDB: 3VRI, 3VRJ, 3UPR) by Illing et al. [15] and Ostrov et al. [16].

Figure 10 displays these time-averaged interactions between the binding pocket of 3UPR (chain A) and peptide P3 (labelled chain P) with either abacavir (Fig. 10a) or acyclovir (Fig. 10b) as histogram plots where the x-axis represent the amino acid and the y-axis represents the Interaction Fraction (IF).

The second pair (41 184) reflects the possible interaction between the binding pocket and the fingers subdomain.

To gain insight into the mode of interaction between the binding pocket and the hydroxylated benzoyl ring, the X-ray crystal structures of YbdB and YdiI in complex with 2,4-DHP-CoA were determined.

Virtual screening of databases was carried out to identify novel compounds on the basis of difference between the binding pockets of the two proteins.

We investigated the selectivity-determining features by gradually mapping the residues deviating between the binding pockets of ALR1 and ALR2 into the ALR2 binding pocket.

Conversely superpose3D finds a structural match comprising eight residues with an RMSD of 0.64 Å. Figure 3 shows the alignment between the binding pockets.

To identify potent and selective dual binding site AChEIs, it was important to know the chemical requirement of these inhibitors and structural differences between the binding pockets of AChE and BChE, respectively.

As indicated in Figure 3g, the interactions between WWOX388−407 and the binding pocket α-helix are hydrophobic (indicated by red dashed lines) and electrostatic (indicated by green dashed lines).

xiap has a ligand that is not anchored in the binding pocket, but binds superficially between two adjacent proteins in the crystal lattice (Fig. 7a).

A comparison between the locked and unlocked conformations indicates that this difference corresponds to specific interactions between the substrate and the binding pocket, which include hydrophobic interactions between a methyl group of triNAG and the side-chain of W109, as well as hydrogen bonds between the ligand and the main chain amide group of N60 and the side chains of W64 and Q104.