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As such, evolution of the transmissibility translates into a difference Δ R0 between the basic reproduction number of the mutated variant and that of the pandemic strain.
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However, the direct relationship between the epidemic threshold and the basic reproduction number is not clearly revealed.
More importantly, according to our method, one can directly determine the relation between the epidemic threshold and the basic reproduction number.
We consider the factors that could affect the spread of the disease including the number of patches, the size of initial infected population, the distance between patches or spatial range, and the basic reproduction number ((R_{0})).
However, the direct relation between the epidemic threshold (lambda_{c}) in [3] and the basic reproduction number (R_{0}) in [20] has not been revealed.
Background: Standard epidemiological theory claims that in structured populations competition between multiple pathogen strains is a deterministic process which is mediated by the basic reproduction number (R0) of the individual strains.
We also provide formulas for individual patch basic reproduction numbers and discuss their connection with the basic reproduction ratio for the system.
Importantly, we find that the basic reproduction number of each strain is independent of the mutation rates between the strains — even under quite general assumptions for the form of the infectious compartment coupling.
The basic reproduction number (Re_{0}) is obtained.
By calculating, we obtain the basic reproduction number (R_{0}).
The basic reproduction number (R_{0}) is obtained.
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