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A ratio was calculated between the average copy number of the BAC probes and of corresponding centromeric probes.
The results were reported as the ratio between the average copy number of the HER2 gene and that of the chromosome 17 centromere, analyzing 20 neoplastic nuclei.
Average copy number for each probe was calculated and the amplification ratio (ratio between the average copy per cell for HER2 and the average copy for centromere 17) determined.
The average copy number for each probe was determined and the amplification ratio was calculated as a ratio between the average copy per cell for HER2 and the average copy number for centromere 17.
In the same way, to see the effect of copy number on gene expression, we also used Spearman's rank to test correlation between the average copy number of a genomic segment and the log2-transformed normalized expression value of a gene overlapping with that genomic segment.
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Taking this in consideration, we corrected the data points for this cell line, using as x-values, the average copy numbers between subpopulations (see dashed trend line in Figure 6).
We found a significant difference in the average copy number between frozen unloaded matched controls and stabilized specimens, detecting 6.92 ± 1.4 log10 copies/mL from frozen unloaded matched controls compared with 6.26 ± 1.1, 6.26 ± 1.2, and 3.93 ± 1.0 log10 copies/mL for DNAstāble Blood tubes, ViveST tubes, and FTA Micro Cards, respectively (P < 0.01).
Moreover, the average copy lengths of overlapping IRs do not differ greatly between the S. cerevisiae genome and its randomizations.
The average copies and weighed communication cost for one content are got.
The averaged copy contains the sum of such attenuated quantization error, hence the total energy of the quantization error in the averaged copy is estimated to be.
However, our analysis revealed that the overall correlation between average copy number and the extent of gene expression was surprisingly weak.
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