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There was no difference in the number of tests between the groups (P=0.812), although the time from diagnosis to the start of testing and the time of intervals between tests were not associated with the results of the CTC tests within the groups (P-values 0.274 and 0.602).
Similar(59)
The appropriate interval between tests is not known (27).
The wide range of days between tests was not controlled for and this may have compromised the validity of the test-retest results.
The variation of HOMA%B index of insulin secretion between tests was not significantly different in the two groups of subjects (16 ± 10% vs. 6 ± 10%, P = 0.49).
Moreover, on D3 post and D4, the change of ratio in between-group tests were not significantly different between pH 7.4 normal saline injection and acidified saline injections.
The change of ratio in between-group tests were not significant on D3 and D4.
Prior to analyses, outliers beyond ± 3.0 z-scores for each neuropsychological variable were curtailed to values of +3.0 or −3.0 (depending on the direction) so that the between-group tests were not skewed by extreme scores [ 63]. (Outliers across the four variables comprised <10% of the sample).
Therefore, considering that the procedure could potentially take a long time given the criteria of 10 repetitions for the closure of this phase baseline trials between the tests were not introduced.
The statistical differences between all tests were not significant (p > 0.05).
Between-group statistical tests were not applied; in fact, due to the large sample size, even trivial differences reached statistical significance.
In all three cases, the high compliance measurements were obtained at P = 0.0000, and the differences between the two tests were not statistically significant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com