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Survival distributions were estimated by the Kaplan Meier method, and the comparison between subgroups was done by the log-rank test.
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Comparisons between subgroups were done using the Pearson Chi-Square test.
The comparison between the subgroups was done by means of t-tests.
Identification of CpG sites that were differentially methylated between tumors and matched tumor-adjacent gastric tissues was performed using the paired sample t-test, while that between methylation subgroups was done using the ANOVA-test.
Analysis of survival times was performed using the method of Kaplan Meier, and comparison of survival between patient subgroups was done by Log-rank test and Cox proportional hazard regression.
Subgroup analysis was done by paired t-test in Excel.
Subgroup analysis was done for NSTEMI/UA and STEMI.
To correct for the small differences in age, smoking status and gender mix between cases and controls, a subgroup (sensitivity) analysis was done (a) limited to those over 60 years of age (age weighting equally applied to all) and (b) where mean age, pack years and gender were closely matched between cases and controls (n = 450: 72 vs 69 yrs, 45 vs 43 pack years and 70% vs 70% male respectively).
The comparison of the mean effect size between subgroups was close to significance (P = 0.06), however, which does not allow one to ensure that the effects of proning were significantly different between subgroups.
For the subgroup analyses, impacts for each subgroup were calculated, and an H-statistic was generated to assess whether the difference in impacts between subgroups was statistically different.
The dichotomy was done to facilitate comparisons between the subgroups.
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CEO of Professional Science Editing for Scientists @ prosciediting.com