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Bias between subgroups was compared using a t-test.
Diagnostic power between subgroups was compared with the χ test and the t-test.
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Disease activity and functional activity between subgroups were compared using Wilcoxon rank sum tests.
Differences in survival between subgroups were compared by log-rank test.
Differences between subgroups were compared using chi square tests and logistic regression analysis.
Continuous variables between subgroups were compared with the Mann-Whitney U test or independent t test, and categorical variables were compared using Pearson's chi-square test.
Scores between subgroups were compared using non-parametric methods, but means are presented because median scores did not show differences between sub-groups.
The Kaplan Meier method was applied to estimate PFS and OS, and differences in outcome between subgroups were compared using the log-rank test.
Actuarial survival curves were estimated using the Kaplan Meier method, and differences in survival between subgroups were compared with the log-rank test and Wilcoxon test.
Differences between subgroups were compared by using the χ2 test or Fisher's exact test when the expected number of events was less than five.
Survival curves were estimated by the Kaplan-Meier method, and the differences in overall survival between subgroups were compared by the log-rank test.
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