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The number of spot treatments for AKs on the face and ears at semiannual study visits and in between study visits was recorded.The number of AKs on the face and ears per participant was not different between the fluorouracil and control groups at randomization (11.1 vs 10.6, P > .10).10
In this study, associations between travel time and missed or delayed visits as well as adherence were not found; however, information on pharmacy or clinic appointments in between study visits was not available.
Of note, the mean study interval between study visits was approximately 4.5 months.
The interval between study visits was adjusted to an annual scale to facilitate the interpretation of rates of LMI, FMI, and BMI decline per year.
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A significant linear correlation between absolute and relative leg volume differences and the difference of exact day time of measurement between the two study visits was found (P <.001).
Attrition by completion of study visits was not different between groups (VLCK diet: 11.1% (5/45), LC diet: 18.2% (8/44); P=0.38/44
Within group changes, between-group differences in overall course and between-group differences at study visits were analyzed using a linear model that takes repeated measures into account (Proc Mixed in SAS), with correction for differences in baseline values.
Study visits were scheduled between 1300 and 1500 hours on weekdays to minimize diurnal variation in BP.
Study visits were standardized to occur between the days 6 and 11 of their menstrual cycles.
All study visits were conducted at the US Department of Agriculture Agricultural Research Service Grand Forks Human Nutrition Research Center.
Regular study visits were scheduled at intervals of 1 month, with weekly telephone contacts between visits.
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