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There were no significant differences between study groups with respect to progression or marked progression, nor was there any influence of duration of follow-up.
There was no statistical difference between study groups with a high heterogeneity level between studies (I2: 85%).
2. Presence of frequent spinal pain does not differ significantly between study groups with varying frequency/severity of TMD symptoms.
The chi-square test and Fisher exact test were used for comparisons between study groups with respect to percentages.
There were no significant differences between study groups with respect to baseline demographic and clinical characteristics (all p-values ≥ 0.057).
Similar analyses will be performed to examine the differences between study groups with regards to an absolute change in A1C ≥ or ≤ 0.5% at 6 and 12 months.
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The median follow-up for total material and for cases below 60 years differed significantly between study groups, and with short follow-up it may therefore be difficult to uncover differences between these 2 concepts.
Results No significant differences between study groups were observed with respect to muscle mass and systolic parameters, such as ejection fraction, fractional shortening, and peak systolic velocity.
Differences between study groups were tested with one-way analysis of variance or Kruskal Wallis as appropriate.
The Mann-Whitney U test was used to compare the promoter methylation between study groups and also with clinicopathological parameters.
Comparisons between study groups were performed with the use of the Mann-Whitney U test.
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