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on associations between study group and AGI were evaluated.
Two-way interactions between study group and other covariates were tested and none were found significant.
**p: comparison between study group and reference group (age < 30 years).
Univariate analysis confirmed that the relationship between study group and the primary outcome was mediated by psychiatric history.
Homogeneity of slopes: p-value for the test for homogeneity of slopes between study group and exposure variable.
The descriptive data and bivariate associations between study group and socio-economic variables are shown in Table 1.
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Primary analysis will compare the incidence of the composite primary outcome between study groups and will be by intention-to-treat.
No association was found between study groups and the Pediatric Risk of Mortality score or length of stay in the cardiac intensive care unit.
There were no significant differences between study groups, no significant changes over time and no interactions between study groups and time of assessment in mean arterial pressure (c); cardiac output (d); systemic vascular resistance (e); and mixed venous oxygen saturation (f).
a Central venous pressure significantly differed between groups (p < 0.001) and changed over time (p < 0.001), without interactions between study groups and time of assessment.
As for additional pulmonary parameters, arterial partial pressure of carbon dioxide significantly increased during the study time (p = 0.001), without differences between study groups, while there were no significant differences between study groups, no significant changes over time, and no interactions between study groups and time of assessment in lung elastance.
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between study design and
between admission group and
between breakaway group and
between study period and
between study condition and
between tissue group and
between study heterogeneity and
between risk group and
between diet group and
between study staff and
between study quality and
between study year and
between intervention group and
between study completion and
between study entry and
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