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Sample size varied between studies with a range from 36 to 462 patients.
Duration of therapy varied markedly between studies with a mean of 9.4 days.
One of the rationale of this definition was to provide a standard definition that could enable better comparisons between studies with a standardized clinical diagnose.
Reported prevalence of psychotropic medications in nursing homes varies substantially between studies with a range of 50%to80%0% of residents with at least one psychotropic medication prescription, depending on the setting, country, and cultural background [ 2].
Moreover, it could be shown that a "significant difference in effect sizes […} between studies with a high or unclear risk of bias and those with a low risk of bias" exists [ 18].
The proportion of males varied more widely between studies with a mean proportion of males of 66% (±19) in the intervention group and 68% (±17) in the control group.
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There was no evidence of a difference in test performance between studies with an adequate, inadequate or unclear reference standard.
A standard χ test was used to assess the presence of heterogeneity between studies, with an α significance level of 0.05 used as an indicator of the presence of significant heterogeneity.
In healthy non-obese individuals, the cardiac lipid content in the fasted state is relatively consistent between studies with an average lipid/water ratio ranging from 0.3 to 0.6 % [ 15, 31– 31].
Unfortunately, many of the techniques used to isolate proteins are essentially disruptive to large protein complexes, and even worse, various popular techniques are disruptive to a different extent, which leads to a disagreement between studies with respect to whether some proteins are stable members of a complex or just demonstrating transient PPIs.
In sporadic AD, the frequency of seizures vary considerably between studies, with more recent reports estimating an incidence of approximately 4 to 5 per 1,000 persons per year [ 2, 3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com