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Common, differentially expressed transcripts or genes between studies were identified with Venny [ 75].
Substantial differences between studies were identified in methods of sampling, extraction, and PCR targets.
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Only 18 studies were identified between the years 2000 and 2014, suggesting that this topic is under-researched.
Studies were identified between January and May 2011 using a PubMed search with a combination of key terms that included: SCIG, IgG, dose, infection and subcutaneous.
Where variations between our findings and those of other studies were identified, these variables were adjusted in the sensitivity analysis.
No case-control studies were identified.
Relevant studies were identified through MEDLINE searches.
Significant predictors of between-study heterogeneity were identified in two of the meta-regression models of outcomes in uncontrolled before-and-after studies.
The potential sources of between studies heterogeneity were identified using meta-regression and sub-group analysis.
The different levels of methylation between studied samples were identified using the two-way hierarchical cluster analysis.
If overlapping study populations were identified between studies, only the most complete one was included in the meta-analysis.
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