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Although most have reported poor overall survival (OS) and progression-free survival (PFS) with tumors expressing high TS levels, the prognostic value of TS expression between studies has not been established[ 10].
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Differences in expression levels between studies have not normally been considered.
It is important to note that the methods between studies have not been uniform and patients have varied by type and severity of illness.
Despite the availability of these large amounts of data, their common content as well as their specific differences, in particular in gene sets between human and rodent studies, has not yet been systematically evaluated.
39, 40 This discrepancy between in vitro and in vivo studies has not been fully explained.
The discrepant results between the two studies have not yet been explained.
While microbiome differences may exist between the sexes, such studies have not been performed in detail.
Although the RTOG 9714 study focusing exclusively on breast and prostate patients is one of the few studies that found a difference in radiation-related toxicities between SF and MF regimens, most studies have not found significant differences in toxicity between SF and MF treatments.
Several studies have reported the functional expression of various chemokine receptors on human MSCs [17] [22]; some of the results are inconsistent between research groups, and many studies have not looked at the full panel of chemokine receptors.
The model of choice is also important; however, the differences between models reported by simulation studies have not always been confirmed by real data analysis.
Moreover, by focusing on changes occurring between fixed (i.e., two-year) periods between observations for all participants, those studies have not been able to estimate aging effects per se.
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