Among these 13 studies that have a direct comparison between presepsin and PCT, seven studies defined the 'gold standard' by the criterions defined in the 1991 ACCP/SCCM consensus conference.
We will explore sources of heterogeneity by comparing the pooled study estimates between subgroups defined by study-level characteristics.
There were statistical differences between survival curves in the study groups (defined by the cutoffs values) for all the genes and times evaluated (P values < 0.05); the exception was represented by the IL2RA expression at B-ALL diagnosis time in children and DEFA1 at time 3 in the high risk subgroups, respectively (P values > 0.05).
7 8 We conducted a systematic literature search of PubMed, PsycInfo and Cochrane databases for studies describing the association between depression (defined by self-reported scales or clinical diagnoses) and dementia incidence published between 1996 through 28 February 2014.
This study investigated the association between SES defined by grade of employment and subclinical coronary artery disease as indexed by CAC, in a well-characterized sample of healthy older men and women.
We also studied whether responses differed between groups defined by demographic characteristics (eg, age, gender, level of education and ethnicity), personal experience with consanguineous marriage and familiarity with genetic diseases.
Additionally, we used Cochran's Q-test to evaluate the statistical evidence for between-study heterogeneity, both within and between the strata defined by smoking status.
The highest degree of overlap between the dataset defined by this study and published proteomics datasets [19] includes six known microneme proteins and four members of the expanded family of PAN domain-containing proteins noted above.
As in our study, they found significant associations between ED (defined by an IIEF-MSM-EF score ≤ 15) and not being in a steady relationship, use of EEPs, and having a more exclusively passive sex role.
We addressed the heterogeneity between studies by defining specific study questions amenable to each type of study, which resulted in three groups.
