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Recent studies of natural nucleotide divergence in a variety of Drosophila genes demonstrated associations between structural polymorphisms in several genes and quantitative traits, including lifespan [4] [6].
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Distinguishing between structural polymorphisms and somatically acquired mutations is a key step towards accomplishing this goal.
The case of the relation between linkage groups 1 and 4 in P. Lilin sheds light on particular aspects of structural polymorphisms in banana.
The maintenance of structural polymorphisms in the Portiera BT genome raises important functional questions.
It is well known that an abundance of structural polymorphisms in malaria parasites contribute to phenotypic diversity.
Non-allelic homologous recombination between paralogous repeats is increasingly being recognized as a major mechanism causing both pathogenic microdeletions and duplications, and structural polymorphism in the human genome.
Although other CNVRs have not been analyzed by qPCR, there is evidence of structural polymorphism in the literature.
In studies focused on the serotonin 1A receptor (HTR1A) gene, Nishiguchi et al. [ 5] found no association between suicide and two structural polymorphisms, Pro16Leu and Gly272Asp in this gene.
Hence the contribution of unknown structural polymorphisms to variation in recombination rates could be significant.
In almost all species no intraspecific numerical or structural polymorphisms between males and females that might indicate the presence of sex chromosomes were detected, although only females were examined in L. costata and P. pictilis and unsexed specimens in 7 other species – see Table 1.
The reviewer raises a valid point concerning our knowledge of structural polymorphisms between the accessions analysed.
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