Microarray studies to detect pathways that cause the difference in phenotype between strains are based on the assumption that the difference in expression of those pathways will be substantial enough to be observable.
The measured strains are based on the installed strain gages.
Pairwise comparisons between strains were conducted using Tukey's Honestly Significant Difference (HSD), based on ANOVAs with vial as a nesting factor, with the sample sizes shown in Table 1 unless noted otherwise.
Scores were based on the temporal overlap between vaccine-induced protection and circulating strains.
The first approach highlighted the differences between the two strains and was based on fold changes (FC) of gene expression between the D-xylonate producing and the control strain with time.
In total, 365,369 targets containing no indels between the two strains were grouped based on the number of SNVs.
Comparison of resistance rate between nosocomial or community-acquired strains and between MRSA and MSSA was based on Chi square test of Pearson or exact test of Fisher according to the distribution; p significant level considered was p < 0.05.
However, because the identified studies overlap considerably with our review, the conclusions about the correlations between stress and strain symptoms seem to be based on most of the relevant studies published before 1995.
SNP clustering was based on strain-strain pair-wise distances computed by counting the number of SNPs that differ between each of the strains divided by the total number of SNPs that are typed in both strains.
The extent to which variance between mouse strains (on which these estimates are based), may be impacted on by factors pertaining to litter or maternal rearing differences is beyond the scope of this study.
