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Both genotypic methods indicate a low diversity between strains isolated from the same sourdough and a higher diversity between strains isolated from different sourdoughs, suggesting an influence of baker practices and/or environmental conditions on the selection of strains.
DNA microarrays have also been employed in order to identify a common core genome differentiating between strains isolated from invasive disease or carriage in three pneumococcal serotypes often found in IPD (6A, 6B and 14 8.
There was no discrete band pattern between strains isolated from different sources; out of twenty strains in subcluster IIb nine were APEC, seven were UPEC of humans and two from dog, one was a human SEPEC and finally the archetypical NMEC strain RS218 grouping within this subcluster.
There were no similarities between strains isolated from different patients.
All pairings were made between strains isolated from the same continent (either North America or Eurasia).
We also found comparable numbers of interspecies recombination events between strains isolated from different hemispheres, or between strains isolated from a limited geographical location (i.e., 9-km coastline in the Miyazaki prefecture).
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Subsequently, Sanger sequencing of the L-aminoacid oxidase gene (aox1) in T. harzianum was applied to determine the mutations differing between various strains isolated from the Trichoderma collection of Koppert Biological Systems.
Moreover GAPDH is virtually identical (>99.6%) among all twelve of the sequenced GAS genomes and in a comparison of GAPDH between GAS strains isolated from both APSGN and non-APSGN patients no obvious differences in expression were found [107].
As described before [ 32], there is a certain variation in the phenotype between HUVEC strains isolated from different donors.
Spoligotyping as well as VNTR typing results suggest a close link between the strains isolated from Algerian cattle and M. bovis strains from mainland Europe.
Further studies regarding the molecular relationships between CPXV strains isolated from humans and from wild or domestic animals would help clarify the epidemiology of this virus.
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